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Affiliations

Eileen M. Foell Chair in Cancer Research

Director of the Center for Advanced Molecular Imaging (CAMI)

Professor of Chemistry

Professor of Biochemistry and Molecular & Cell Biology

Professor of Neurobiology & Physiology

Professor of Radiology

Charles Deering McCormick Professorship of Teaching Excellence

Chemistry of Life Processes Institute (CLP)

Research Statement

The Meade Lab research focuses on inorganic coordination chemistry for the study of molecular imaging of in vivo gene expression and intracellular messengers, transition metal enzyme inhibitors, and electronic biosensors. The design, synthesis and physical properties of transition metal and lanthanide coordination complexes are the foundation of our research.

Selected Publications

Mitrut RE, Stranford DM, DiBiase BN, Chan JM, Bailey MD, Luo M, Harper CS, Meade TJ, Wang M, Leonard JN, J Extracell Vesicles. 2024 Jul; 13(7): e12469-.

Kaster MA, Caldwell MA, Meade TJ,  Inorg Chem. 2024 May; 63(21): 9877-9887.

Tang J-H, Li H, Yuan C, Parigi G, Luchinat C, Meade TJ, J Am Chem Soc. 2023 May; 145(18): 10045-

10050.

Kaster, M.; Levasseur, M.; Edwardson, T.; Caldwell, M.; Hofmann, D.; Licciardi, G.; Parigi, G.; Luchinat, C.; Hilvert, D.; Meade, TJ. ACS Applied Bio Materials, 2023, ASAP.

Edited by Meade, TJ. ISBN 9781032135786. Published September 27, 2022 by CRC Press.

Dukes, M.; Modo, M.; Meade, TJ. CRC Press, 2022; pp 261-286.

Dukes, M.; Meade, TJ. Biomedicines, 2022, 10, 2376.

Dukes, M.; Bajema, E.; Whittemore, T.; Holmgren, R.; Meade, TJ. Bioconjugate Chem., 2022, 33, 643–653.

Brue, C.; Dukes, M.; Masotti, M.; Holmgren, R.; Meade, TJ. ChemMedChem, 2022, 17, e2022000.

Li, H., Lou, D., Yuan, C., Wang, X., Wang, J., Basilion, J., Meade, T.J., “.”  J. Am. Chem. Soc., (2021), 143, 17097–17108.

Taghian, T., et al., “.” Molecular Therapy: Methods and Clinical Development., (2021), 29, 128-134.

Adams, CJ., Meade, TJ., “.” Chem. Med. Chem. (2021), 16, 1-10.

McLeod, SM., Meade, TJ., “.” Metal Ions in Life Sciences, (A. Sigel, E. Freisinger and R. Sigel, eds.) Vol. 22, (2021), 347–370.

Adams, CJ., Meade, TJ., “Imaging Bacteria with Contrast-Enhanced MR.” Metal Ions in Life Sciences., (A. Sigel, E. Freisinger and R. Sigel, eds.) Vol. 22, (2021), 425-435.

Lilley LM, Kamper S, Caldwell M, Chia ZK, Mallweg D, Vistain L, Krimmel J, Mills TA, MacRenaris K, Lee P, Waters EA, Meade TJ. “.” Angew Chem Int. Ed. Engl., (2020), 59, 388-394.

Adams C., Meade TJ., “.” Chemical Science, (2020), 11, 2524-2530.

Long, Yi-Tao., Meade, TJ., “.” Chemical Science, (2020), 11, 6940-6941.

Adams C., Krueger R., Meade TJ.,“." ACS Chemical Biology, (2020), 15, 334-341.

McLeod, SM, Robison, L., Parigi, G., Olszewski, RJ., Drout, X., Gong, TI., Luchinat, C., Farha, O., Meade, TJ., “.” ACS Applied Materials & Interfaces, (2020), 12, 41157-41166.

Roberts, KF., Brue, CR., Preston, A., Baxter, D., Herzog, E., Varelas, E., Meade, TJ., “.” J. Inorg. Biochem., (2020), 213, 111265-111275.

Luo, D., Johnson, A., Wang, X., Li, H., Erokwu, BO., Springer, S., Jason Lou, J., Ramamurthy, G., Flask, CA., Clemens Burda, C., Basilion, JP., Meade, TJ., “.” Nano Letters, (2020), 20, 7159-7167.

Caldwell, MA., Brue, CR., Whittemore, TJ., Meade, TJ., “.” RSC Advances, (2020), 10, 8994–8999.

Adams C., Meade TJ., “Gd(III)-Pt(IV) .” Chemical Science, (2020), in press. 

Adams C., Krueger R., Meade TJ.,“." ACS Chemical Biology, (2020), in press.

Lilley LM, Kamper S, Caldwell M, Chia ZK, Mallweg D, Vistain L, Krimmel J, Mills TA, MacRenaris K, Lee P, Waters EA, Meade TJ. “” Angew Chem Int.Ed Engl., (2020), 59, 388-394. PMCID: PMC6923588.

Li H, Meade TJ. “” J. Am. Chem. Soc., (2019), 141, 43, 17025-17041. PMCID: PMC6821590.

Moore LK, Caldwell MA, Townsend TR, MacRenaris KW, Moyle-Heyrman G, Rammohan N, Schonher EK, Burdette JE, Ho D, Meade TJ. “” Biocon. Chem., (2019), 30, 2947-2957. PMCID: PMC6868311.

Iscen A, Brue CR, Roberts KF, Kim J, Schatz GC, Meade TJ. J. Am. Chem. Soc., (2019), 141, 16685-16695.

Bajema EA, Roberts KF, Meade TJ, " (A. Sigel, E. Freisinger and R. Sigel, eds.) Vol. 19., Chapter 11, (2019), 4267-4301.

Li H, Parigi G, Luchinat C, Meade TJ. J. Am. Chem. Soc., (2019), 141 (15), 6224-6233 DOI: PMCID: PMC6939894.

Hanson, ED., Lilley LM., Cain JD., Shiqiang H., Palacios E., Aydin K., Wolverton C., Meade TJ., Dravid, VP., “ Materials Chemistry and Physics, (2019), 225, 219-226. 

Rotz MW, Holbrook RJ, MacRenaris KW, Meade TJ. "" Bioconjugate Chemistry, (2018), 29, 11, 3544-3549. PMCID: PMC6268127.

LM Lilley, K Du, MD Krzyaniak, G Parigi, C Luchinat, TD Harris and TJ Meade.   Inorg Chem (2018), 57(10), 5810-5819. PMCID: PMC6016852.

Sleep E, Cosgrove BD, McClendon MT, Preslar, AT, Chen CH, Sangjie MH, Perez CMR, Haynes  RD, Meade TJ, Blau HM, Stupp SI. PNAS (2017), 114(38), E7919-E7928. PMCID: PMC5617293.

Selected Honors / Awards

• Investiture: The Charles McCormick Professor of Teaching Excellence, NU (2021)
• World Molecular Imaging Society Gold Medal Award for Pioneering Imaging (2020)
• Gold Medal Award for Molecular Imaging: California Institute of Technology (2020)
• George Fisher Baker Lecturer, Department of Chemistry, Cornel University (2019)
• Fellow, National Academy of Inventors (2017)
• Stony Brook University Franklin Award Lecture (2017)
• Mahler Lecturer, University of Texas, Austin (2016)
• Fellow, Royal Society of Chemistry (2016)
• Associate Editor, Chemical Science (2016)
• Elected Fellow, National Academy of Inventors (2016)
• Elected Fellow, Royal Society of Chemistry (2016)
• The J. Stieglitz Award: University of Chicago and the American Chemical Society (2016)
• Elected Fellow, American Association of Advancement of Science (2015)
• Hill Lecturer, Duke University (2014)
• Catalyst Award, ±¬ÁϳԹÏÍø and the City of Evanston (2014)
• Fellow of the World Molecular Imaging Society (2012)
• Fellow of the American Chemical Society (2011)
• Society for Molecular Imaging Annual Exceptional Achievement Award
• Musselman Award for Visiting Scientist (2010)
• Illinois Biotechnology Industry Organization (iBIO) iCON Innovator Award (2009)
• Miller Professor, University of California Berkeley (2009)
• ±¬ÁϳԹÏÍø Excellence in Teaching Award (2008)
• William Beaumont Award: Wayne County Medical Society (2007)
• Allen & Constance Ford Distinguished Award, CaseWestern ReserveUniversity (2006)
• Eileen Foell Chair in Cancer Research, ±¬ÁϳԹÏÍø, (2005)
• Elected President – Society of Molecular Imaging - Membership>1,000 Chair (2005)
• Committee - Imaging in 2020 IV, (2005)
• FMC Award - Princeton University, (2004)
• Elkin Distinguished Investigators Cancer Lecturer, Emory University (2003)
• Neuroscience Award Lecture, Society for Neuro-Oncology (November 2002)
• National Academy of Engineering Lecturer, Cleveland, Ohio, (2000)